Our new Obvious+ tissue clearing approach is the one strategy that delipidates samples without any adjust in morphology and with small influence on structural integrity.
Megatome is usually a vibrating microtome designed to segment a broad number of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With higher blade vibrating frequency and minimized blade deflection, Megatome enables large-throughput tissue sectioning with uniform floor profile, and also small tissue destruction and knowledge decline.
Antibodies may possibly just take months to diffuse by way of just a few millimeters of tissue, by using a steep labeling gradient from area to Main.
Megatome is suitable for accuracy: the blade vibrates at a greater frequency and larger amplitude variety than other microtomes, and features a distinctive deflection control mechanism.
Clone the job or get the most recent release. Running the utility will change a little bit dependant upon how you retrieve the venture.
Our preformulated EasyIndex Answer raises and homogenize the refractive index of delipidated tissue samples, rendering them completely transparent. This enables light-weight penetration in to the sample and makes sure the acquisition of significant-resolution, in-emphasis picture data.
Megatome is really a novel microtome which allows for prime-precision sectioning of a wide range of tissue samples – from organoids, to arrays of animal organs, to intact human Mind megatomi.com hemispheres – with small tissue hurt and information loss.
It’s time for you to enhance your microtome to Megatome. With precise superior-frequency slicing for an unmatched selection of sample dimensions and types – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for varied programs.
The SmartSPIM light sheet microscope supplies unparalleled resolution and acquisition speed through intact tissue volumes, while its modular style and design enables you to up grade and customize particular person components.
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This could deliver a feed directory inside the javadoc2dash.outputLocation Listing. This directory will have an XML file describing the feed
Either obtain a launch or create a distribution zip as outlined previously mentioned. Unzip the archive to your desired area.
Leverage the Crystal clear+ tissue clearing method, together with eFLASH and patented stochastic electrotransport technologies, to quickly obvious and label total organs. Vital highlights and features contain:
Our novel Defend tissue preservation procedure sorts intramolecular bonds using polyfunctional, flexible epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.